MERGING CLASSICAL PHARMACEUTICS WITH CUTTING EDGE INNOVATION AND TECHNOLOGY

AM-IMG_9402-scaled

PREFORMULATION SERVICES

• API Physical and Chemical Characterization
• Excipient Compatibility Studies conducted with multiple API’s if necessary and excipient functionality categories
• Particle Size Distribution
• Polymorph screen studies
• Partition coefficient studies
• Thermal analysis interpretation

Bravado Pharm. FDA registration #  3015234532  DBPR # 20380

FORMULATION DEVELOPMENT STUDIES

• High Shear wet granulation
• Hobart “medium” shear wet granulation
• Fluid Bed top spray wet granulation
• Fluid Bed bottom spray wet granulation
• Fluid Bed drying multiple units
• Dry Granulation/Roller compaction
• V-shell dry blending
• Octagonal Bin tumbler dry blending
• Encapsulation via various techniques
• Coating via conventional pan and bottom spray wurster techniques
• Bi-layer fully instrumented tableting with micro-tablet capabilities
• Lyophilization capability
• Lightnin type impeller mixers, homogenizers and various mixing vessels for liquid and semi-solid dosage forms

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CoVer bottle IMG_0965

FORMULATION SUPPORT AND ANALYTICAL DEVELOPMENT

• Analytical method development for stability indicating methods via HPLC

• Stability storage at ICH condition via various analytical techniques testing developed products both physically and chemically

• Stability studies conducted under protocol with stability calendars

• Stability chambers 25°C/60% RH, 30°C/65% RH, 40°C/75% RH. Custom conditions can be utilized at client request

PILOT SCALE AND CLINICAL MANUFACTURING

• Solid oral (tablet, capsule). Tablets in multiple platforms including multi-layer and micro. Capsules in both solid fill and multi-particulate. Micro-tablets in capsules 
• Liquid oral (solution, suspension and emulsions)
• Topical (lotions, ointments, creams and gels)

boxes
pills

PACKAGING

• Universal Packaging Systems, Inc. unit dose blister pack machine.
• Solids, liquids and semi solids manual operation for small studies with automated units to be acquired as needed.